Modulating Glucosides: Advanced Comfort for Skin

The skin barrier plays a central role in maintaining the skin’s equilibrium, yet it can sometimes be disrupted, leading to visible redness, discomfort, or heightened reactivity. Supporting your skin’s barrier under these conditions requires a formulation that addresses both visible signs of irritated skin and your skin’s resilience.

NIOD Modulating Glucosides (MG) was created with this in mind. The alcohol-free formulation combines bio-active glucosides with barrier-supporting technologies to help reduce visible signs of reactive skin while reinforcing the skin’s resilience. Below, we examine the science behind MG, the benefits it provides, and how it can fit within a daily regimen to support healthy-looking skin.

What Are Modulating Glucosides?

At its core, MG is centred on modulation: the process of guiding the skin’s responses towards balance rather than suppressing them. This approach works at a foundational level to reduce the persistence of visible irritation. Through a considered blend of technologies, MG helps to return the skin to a state of equilibrium.

The formula stands apart by not simply offering symptomatic relief but by working to support the skin's responses over time. The result is improved resilience and a complexion that appears visibly calmer and less reactive.

Key Technologies in Modulating Glucosides

MG's efficacy is the result of a carefully formulated blend of advanced skin technologies, each playing a specific role in supporting the skin's integrity and comfort:

Targets Visible Redness and Discomfort:

  • Multi-Molecular-Lipid Complex: A blend of Oat Synthetic Analogues, Ceramides, Purified Ginger Root and other dermal-friendly lipids
  • Propyl Gallate, Gallyl Glucoside, and Epigallocatechin Gallatyl Glucoside: This trio of compounds offers a soothing effect
  • Palmitoyl Tripeptide-8: This innovative peptide is designed to offer a calming effect by helping to visibly soothe skin.
  • Tasmannia Lanceolata Fruit/Leaf Extract: An ingredient known for its soothing properties, this extract helps to soothe signs of redness in the skin. It also helps to alleviate sensations of discomfort, providing a soothing effect.
  • Soothing Complex: This potent blend of ingredients, including 4-t-Butylcyclohexanol, Bisabolol, Cetylhydroxyproline Palmitamide, Hydroxyphenyl Propamidobenzoic Acid, Stearic Acid, Brassica Campestris (Rapeseed) Sterols, and Zingiber Officinale (Ginger) Root Extract, delivers a pronounced soothing effect.

Skin Barrier Support:

  • Curculigo Orchioides Root Extract: This powerful botanical extract helps to support and maintain the integrity of the epidermal barrier. By supporting the skin's first line of defence, it can help reduce the skin's visible signs of skin reactivity over time.
A Systems Approach to Skin Comfort

What distinguishes Modulating Glucosides is the blend of its technologies. The formula works on multiple fronts simultaneously: addressing the sensation of discomfort, significantly reducing reactivity and sensitivity of the skin, and reinforcing the skin's barrier. It is a proactive solution for skin comfort, suitable for all skin types, designed to build resilience rather than simply mask symptoms.

The Benefits of Modulating Glucosides

The benefits of MG go far beyond a simple calming effect. They translate into visible, lasting improvements towards healthy-looking skin and comfort:

  • Minimise visible redness: Through its targeted modulation technologies, MG is designed tohelp reduce the appearance of visible redness. Ingredients in this formula help contribute to a more even, calm-looking complexion over time.
  • Enhances skin comfort: Feelings of tightness can profoundly impact daily comfort. MG directly addresses these sensations, providing a feeling of relief. 
  • Supports barrier function: A compromised epidermal barrier is at the root of many skin concerns. By utilising ingredients like Curculigo Orchioides Root Extract, MG helps to support and strengthen this barrier, contributing to reduced trans-epidermal water loss (TEWL) and a more resilient barrier.
  • Addresses discomfort & itching: The formula's blend of soothing agents, including Tasmannia Lanceolata, works to help alleviate signs of irritation and discomfort, making it an effective solution for visible signs of skin reactivity.

Integrating Modulating Glucosides into your Regimen

Modulating Glucosides (MG) is especially suited to skin that is reactive, redness-prone, or easily sensitised. It also provides essential support for those navigating environmental irritants or incorporating more intensive actives into their skincare routine, helping reinforce the skin’s barrier when it needs it most.

How to use Modulating Glucosides

Apply a few drops to the face, morning and evening. Use after cleansing and before anhydrous (water-free) serums, oils, suspensions, or creams. If irritation occurs, discontinue use and consult a physician. Use only as directed on unbroken skin. Patch testing prior to use is recommended. Keep out of reach of children.

When to use Modulating Glucosides

Morning

  1. Cleanse
  2. Apply Copper Amino Isolate Serum
  3. Apply Modulating Glucosides
  4. Apply Multi-Molecular Hyaluronic Complex
  5. Follow with any additional formulations as needed

Evening

  1. Cleanse
  2. Apply Copper Amino Isolate Serum
  3. Apply Modulating Glucosides
  4. Apply Multi-Molecular Hyaluronic Complex
  5. Finish with any night-specific formulations as needed

For enhanced results, MG can be layered with other NIOD or existing skincare products. It pairs well with hydration serums like NIOD Multi-Molecular Hyaluronic Complex to provide both soothing and deep hydration. 

While some soothing effects may be felt immediately, the more significant results of barrier support and reduced reactivity will build with consistent, long-term use.

What to Expect from Modulating Glucosides

Customers who have integrated Modulating Glucosides into their routines often speak of a profound, lasting change. They describe their skin as feeling "calmer" and "less reactive" over time, noting a significant reduction in visible redness and signs of irritation. The feedback consistently highlights the product's ability to not just mask a problem, but to contribute to a healthier-looking, more resilient state for the skin. Many find that it has been the missing piece in their routine, providing a level of comfort they had long been seeking.

Here are some customer reviews:

Incredibly gentle and non-irritating.

“The formula is incredibly gentle and non-irritating, making it ideal for sensitive or reactive skin like mine. From the moment I applied it, I noticed how smooth and soothing it felt. It absorbs quickly without any greasy or heavy residue, which I love. Most importantly, it immediately helped calm the redness [] I was dealing with. It provided the relief I needed and supported my skin barrier during a time when my skin was feeling dry and irritated, and uncomfortable.” - Dawness

Amazing for redness!

“I have been so impressed with this product. I’ve implemented it into my nighttime skincare routine for about 2 weeks now and it has made an incredible difference in the redness! Best of all, it didn’t irritate my sensitive skin in the slightest! I’m loving it.” - Rhendz

Toward Comfort, Balance and Resilience

Modulating Glucosides offers a considered approach to reducing visible redness and signs of reactivity. Applied with consistency, it supports comfort, balance and resilience as part of skin’s long-term function.

Incorporate Modulating Glucosides into your regimen to reduce skin’s reactivity, strengthen the barrier and support resilient skin.