MMHC2: Precision Hydration

Our bestseller, NIOD Multi-Molecular Hyaluronic Complex (MMHC2), was developed to meet this need with precision, delivering a future-lensed hydration system built from 15 advanced hyaluronic technologies. By combining multiple molecular weights of hyaluronic acid with advanced supporting technologies, it enhances water balance at different levels of the skin surface. The effect is immediate comfort you can feel, alongside a foundation for lasting suppleness over time.

Take a closer look at what makes MMHC2 distinct, who it serves best, and how it can become an important step in a skincare regimen designed for skin optimisation.

MMHC2 is built on the understanding that different molecular weights of hyaluronic acid perform distinct functions within the skin. Smaller molecules absorb more readily than larger molecules and provide deeper hydration while larger molecules remain at the surface where they perform similar functions. Both are necessary to support optimal skin hydration.

MMHC2’s tri-fold approach to hydration:

• Topical delivery: A range of molecular weights of sodium hyaluronate, together with direct hyaluronic acid, delivers hydration across multiple surface layers while contributing to the look of plumpness.
• HA-like polymers: Polymers that mirror the structure of hyaluronic acid, but with enhanced water-retention capacity, provide lasting moisture and fortify barrier function.
• HA precursors: Compounds that encourage the skin’s own production of hyaluronic acid, supporting sustained hydration.

15 Hyaluronic Acid & Complementary Technologies

At the core of MMHC2 is a complex of 15 hyaluronic acid and HA-complementary technologies featuring different molecular weights. This multi-layered system works to mimic and amplify the skin’s own hyaluronic acid, reinforcing its natural ability to retain water. The result is a smoother texture, plumper and more hydrated appearance.

MMHC2 has been conceived as a universal formulation for hydration, making it appropriate for every skin type. The water-based serum is especially valuable for skin dryness or dullness, and complexions marked by age-related changes in texture. By supporting hydration across multiple layers of the skin, MMHC2 helps to visibly plump fine lines, rehydrate dry skin and contribute to the preservation of bounce and suppleness over time.

For those who seek advanced formulations built on scientific precision and measurable efficacy, MMHC2 goes beyond topical hydration supplementation, and supports skin’s own natural production of hyaluronic acid while helping to minimize its depletion.

Apply MMHC2 early in your routine so it can support the absorption of what follows. Here’s how to layer it:

1. Cleanse your skin.
2. Apply MMHC2.
3. Continue with anhydrous (water-free) serums, oils, suspensions, or creams.

Layer MMHC2 with these NIOD products:

• For healthy-looking skin or ageing concerns: Use with Copper Amino Isolate Serum 3 1:1 (CAIS3). Apply CAIS3 first, allow it to absorb, and follow with MMHC2 to support elasticity and healthy-looking skin.
• For advanced hydration: Layer MMHC2 as a foundational step before emollient or barrier-support formulation. We recommend Hydration Vaccine to not only add, but preserve moisture. 
• For radiance and refinement: Combine with antioxidant formulations to enhance brightness and protect against the visible effects of oxidative stress. We recommend: Superoxide Dismutase 3 Enzyme Mist (SDEM3), NIOD’s protective antioxidant face mist that prevents visible skin damage before it occurs.

Do Not Combine With:

• Direct Acids
• Direct Vitamin C
• Resveratrol and Ferulic Acid
• Salicylic Acid

Separating these formulations within a regimen allows MMHC2 to perform optimally while maintaining the integrity of all treatments.

As a next-generation hydration serum, MMHC2 was designed not only to replenish moisture but to work in synergy with the skin’s own processes. The benefits extend across hydration, texture, and resilience.

Key Benefits

• Three-tiered hydration:  A comprehensive system that delivers moisture throughout the surface layers of skin while supporting the skin’s own ability to sustain hydration.
• Topical supplementation: Multiple molecular weights of hyaluronic acid provide visible plumping and offer hydration across different layers of the skin.
• Occlusive performance: Clinical testing* has shown MMHC to be comparable to petroleum jelly in maintaining skin hydration levels within 15 minutes of application.  This is achieved in a lightweight texture that avoids heaviness while still preserving moisture retention.
• Support for natural HA production: Ingredients in MMHC2 help maintain and support the skin’s own hyaluronic acid levels, contributing to visible plumpness, and resilience.

*In a clinical study of 18 subjects conducted in-house.

Customer Perspectives

MMHC2 is a NIOD bestseller, consistently praised for its ability to transform the feel and appearance of skin, from softening the look of fine lines to restoring radiance and suppleness.

Here are some customer reviews:

Smooth & supple skin!
“I’ve been loving the NIOD Multi-Molecular Hyaluronic Complex. It’s helped improve my skin texture and tone to make it more smooth and bright.” - HeySpencer

The best hyaluronic serum I tried so far.
“It feels really good on skin and has some plumping effect - the skin feels soft, moisturised and looks really good.” - Dasha

MMHC2 represents a future-facing approach to hydration that extends far beyond the limits of basic hyaluronic acid. Through 15 advanced hyaluronic technologies combined with complementary actives, it delivers immediate comfort, visibly plumps fine dry lines, enhances smoothness and radiance, and reinforces long-term resilience. For those invested in advanced skin function, MMHC2 offers a precise system designed to measurably enhance the skin’s own capacity to retain and regulate moisture.

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